It is very commonly known as asthisamharaka. Cissus has been used in various ayurvedic classical medicines to heal broken bones and injured ligaments and tendons. Bone setter has been used as a medicinal plant since antiquity. In siddha medicine it is considered a tonic and analgesic, and is believed to help heal broken bones, thus its name asthisamharaka (that which prevents the destruction of bones). It is said to have antibacterial, antifungal, antioxidant, anthelmintic, antihemorrhoidal and analgesic activities. It has been found to contain a rich source of carotenoids, triterpenoids and ascorbic acid. Its bactericidal effects on Helicobacter pylori hold promise as a potential treatment of gastric ulcers in conjunction with NSAID therapy. A weight loss supplement containing Cissus quadrangularis and other ingredients including green tea, soy, selenium, chromium, and B vitamins was evaluated in an 8-week trial. The supplement helped reduce body weight by 4-8% ( placebo 2.4%) a clinically significant weight loss. The juice of Edible stemmed vine, Bone setter is used to grind the pills and it is also used in the preparation of the medicated oil, used in the treatment of toxicology
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